Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770444 | 0.90 | ALDH1A1 (0.47) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2862851 | 0.85 | MEN1 (0.56) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL4361591 | 0.84 | MEN1 (0.61) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2866072 | 0.82 | KMT2A (0.61) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2868355 | 0.81 | MEN1 (0.58) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2868549 | 0.81 | KMT2A (0.51) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2866075 | 0.80 | MEN1 (0.56) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2869502 | 0.79 | MEN1 (0.61) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL13956774 | 0.77 | MEN1 (0.66) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL2866249 | 0.77 | KMT2A (0.58) | MEN1KMT2ARAB9AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087755-A | Substituted arylacylthioureas and related compounds; inhibitors of viral replication | ACHILLION PHARMACEUTICALS INC (US) | 2007-12-12 | — | — | CN | claimed |