Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19313567 | 0.79 | HTT (0.39) | NR2E3MAPK14ALDH1A1MAPT | |
| SCHEMBL19356577 | 0.78 | MAPK14 (0.38) | NR2E3MAPK14ALDH1A1 | |
| SCHEMBL20170593 | 0.78 | ALDH1A1 (0.38) | MAPK14ALDH1A1 | |
| SCHEMBL18672244 | 0.77 | HTT (0.37) | NR2E3MAPK14ALDH1A1MAPT | |
| SCHEMBL18672227 | 0.77 | MAPK14 (0.38) | NR2E3MAPK14ALDH1A1MAPT | |
| SCHEMBL18672225 | 0.77 | HTT (0.37) | NR2E3MAPK14ALDH1A1MAPT | |
| SCHEMBL18401357 | 0.76 | MAPK14 (0.36) | NR2E3MAPK14ALDH1A1GAA | |
| SCHEMBL18672242 | 0.76 | NR2E3 (0.35) | NR2E3MAPK14ALDH1A1MAPT | |
| SCHEMBL2180167 | 0.74 | KMT2A (0.61) | KDM4EALDH1A1MAPTGAA | |
| SCHEMBL18672247 | 0.73 | GRM2 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-85108650-A | The preparation method of pyridazinone derivative, and insecticidal constituent kill acaricidal composition, and the nematicide composition kills (very) bacterium composition | — | 1986-09-24 | — | — | CN | disclosed |