Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.62 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 7/20 | 0.53 |
| ▸ | JAK2 | O60674 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.51 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.51 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5225654 | 0.80 | ROCK2 (0.72) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL30933139 | 0.80 | ROCK2 (0.72) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL5823137 | 0.80 | ROCK2 (0.63) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL10310329 | 0.80 | ROCK2 (0.63) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL2565558 | 0.77 | ROCK2 (1.00) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL21341425 | 0.76 | ROCK2 (0.58) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL1163706 | 0.75 | ROCK2 (0.74) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL20611859 | 0.75 | ROCK2 (0.64) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL5564049 | 0.74 | MKNK1 (0.60) | ROCK2ROCK1NPC1RAB9AJAK2 | |
| SCHEMBL2569041 | 0.74 | ROCK2 (0.63) | ROCK2ROCK1NPC1RAB9AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-88100129-A | The preparation method of sweeting agent guanidoacetic acid and ethanamidine guanidine-acetic acid derivative and the prescription that contains this class sweeting agent | — | 1988-07-27 | — | — | CN | disclosed |