⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10502952 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL4619363 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL104136 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL10503195 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL103685 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL10503416 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL277022 | 0.97 | — | — | |
| SCHEMBL10502676 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL10502961 | 0.97 | TSHR (0.50) | — | |
| SCHEMBL10503065 | 0.97 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 549 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | claimed |
| EP-3791724-A1 | TREATMENT OF BREAST CANCER | Medivation Prostate Therapeutics LLC (US) | 2021-03-17 | — | — | EP | claimed |
| US-20210069154-A1 | Treatment of Breast Cancer | MEDIVATION PROSTATE THERAPEUTICS LLC | 2021-03-11 | — | — | US | claimed |
| EP-3610731-A1 | TREATMENT OF BREAST CANCER | Medivation Prostate Therapeutics LLC (US) | 2020-02-19 | — | — | EP | claimed |
| US-10434182-B2 | Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2019-10-08 | — | — | US | claimed |
| EP-3430907-A1 | TREATMENT OF BREAST CANCER | Medivation Prostate Therapeutics LLC (US) | 2019-01-23 | — | — | EP | claimed |
| US-20180214561-A1 | EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2018-08-02 | — | — | US | claimed |
| EP-3315531-A1 | 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY | Xiamen Sinopeg Biotech Co., Ltd. (CN) | 2018-05-02 | — | — | EP | claimed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | claimed |
| US-9126962-B2 | Substituted phenylcarbamoyl alkylamino arene compounds and N,N′-BIS-arylurea compounds | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-09-08 | — | — | US | claimed |
| WO-1995018127-A1 | AZA-4-IMINOQUINOLINES, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-06 | — | — | WO | claimed |
| EP-0657166-A1 | Combination containing a quinoxaline and a nucleoside | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-14 | — | — | EP | claimed |
| EP-0590428-A1 | Azaquinoxalines, process for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-06 | — | — | EP | claimed |
| EP-0579968-A1 | 4-Iminoquinolines, processes for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-01-26 | — | — | EP | claimed |
| US-5270153-A | Cyan image forming method and silver halide color photographic material containing cyan coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-14 | — | — | US | claimed |
| US-5256526-A | Form high color density colorfast images | FUJI PHOTO FILM CO., LTD. (JP) | 1993-10-26 | — | — | US | claimed |
| EP-0509398-A1 | Quinoxalines, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-10-21 | — | — | EP | claimed |
| EP-0491197-A1 | Cyan image forming method and silver halide color photographic material containing cyan coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-24 | — | — | EP | claimed |
| EP-0488248-A1 | Cyan image forming method and silver halide color photographic material containing cyan coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-03 | — | — | EP | claimed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |