Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL1423596 | 0.97 | TP53 (0.43) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL372201 | 0.97 | TP53 (0.43) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL27484901 | 0.94 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL28226117 | 0.94 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL5024454 | 0.94 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL797742 | 0.92 | TP53 (0.39) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL18188066 | 0.92 | TP53 (0.39) | TP53PSIP1LMNACA12CA1 | |
| Butane SCHEMBL2218261 | 0.88 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Butane SCHEMBL3883260 | 0.88 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL3691305 | 0.87 | TP53 (0.36) | TP53PSIP1LMNAPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101039683-A | Compositions and methods using hyaluronic acid and hyaluronidase inhibitors | ANGIOTECH INT AG (CH) | 2007-09-19 | — | — | CN | disclosed |