Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL1423596 | 1.00 | TP53 (0.43) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL28226117 | 0.97 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL27484901 | 0.97 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL27693170 | 0.97 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL5024454 | 0.97 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL797742 | 0.94 | TP53 (0.39) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL18188066 | 0.94 | TP53 (0.39) | TP53PSIP1LMNACA12CA1 | |
| Butane SCHEMBL2218261 | 0.91 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Butane SCHEMBL3883260 | 0.91 | TP53 (0.41) | TP53PSIP1LMNACA12CA1 | |
| Propane SCHEMBL3691305 | 0.89 | TP53 (0.36) | TP53PSIP1LMNAPCSK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327007-A | VT107 preparation method | 上海陶术生物科技有限公司 | 2024-01-02 | — | — | CN | claimed |
| CN-110372493-B | Method for synthesizing diflunisal and derivatives thereof by one-step method | 北京师范大学 | 2020-09-08 | — | — | CN | claimed |
| CN-110437159-A | The preparation method of antagonists of gonadotropin-releasing hormone intermediate and antagonist sodium | LIVZON NEW NORTH RIVER PHARMACEUTICAL CO LTD | 2019-11-12 | — | — | CN | claimed |
| CN-106995461-B | A kind of Phosphine ligands of the structure containing benzofuran and its preparation method and application | 中山大学 | 2019-11-08 | — | — | CN | claimed |
| CN-108067632-B | A kind of method and application preparing noble metal orphan's atom in the solution | 中国科学院大连化学物理研究所 | 2019-11-08 | — | — | CN | claimed |
| CN-110372469-A | Hydrogenate annulus [12] aromatic compound and preparation method thereof | 清华大学 | 2019-10-25 | — | — | CN | claimed |
| CN-110372608-A | A kind of preparation method of antagonists of gonadotropin-releasing hormone | 丽珠集团新北江制药股份有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-110359097-A | The method that On-DNA aromatic compound is obtained by Suzuki coupling reaction in the building of DNA encoding compound library | 上海药明康德新药开发有限公司 | 2019-10-22 | — | — | CN | claimed |
| CN-110331447-A | The method of On-DNA aryl acetylene hydrocarbon compound is prepared in the building of DNA encoding compound library | 上海药明康德新药开发有限公司 | 2019-10-15 | — | — | CN | claimed |
| CN-110272386-A | Preparation method of nodispat | 上海医药集团股份有限公司 | 2019-09-24 | — | — | CN | claimed |
| CN-108276421-A | A kind of synthetic method of Wei Patawei | 浙江永太药业有限公司 | 2018-07-13 | — | — | CN | claimed |
| CN-105294573-B | A kind of method for synthesizing 4,6- bis- chloro- 2- (rosickyite base) -5- aminopyrimidines | 厦门医学院 | 2018-07-10 | — | — | CN | claimed |
| CN-108250191-A | A kind of disubstituted 2- amino-pyrazinos compound of 3,5- and its preparation process and application | 兰州大学 | 2018-07-06 | — | — | CN | claimed |
| JP-4795589-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| EP-1272500-B1 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES | ABBOTT LAB (US) | 2005-05-04 | — | — | EP | claimed |
| EP-1272500-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSITUTED ERYTHROMYCIN DERIVATIVES | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| US-6437106-B1 | ALKYLATION WITH ALKENYL CARBONATE OR CARBAMATE IN PRESENCE OF PALLADIUM CATALYST AND PHOSPHINE; CYCLIZATION | ABBOTT LABORATORIES | 2002-08-20 | — | — | US | claimed |
| WO-2001025179-A1 | PREPARATION OF TETRACYCLIC INTERMEDIATES | INSTITUTE OF DRUG TECHNOLOGY AUSTRALIA LIMITED (AU) | 2001-04-12 | — | — | WO | claimed |
| WO-2000078773-A2 | PROCESS FOR PREPARING 6-O-ALKENYL-SUBSTITUTED ERYTHROMYCIN DERIV ATIVES | ABBOTT LABORATORIES (US) | 2000-12-28 | — | — | WO | claimed |
| EP-0627399-B1 | Process for producing 2-formyl-1,4-butanediol | KURARAY CO (JP) | 1997-03-19 | — | — | EP | claimed |