Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 3/20 | 0.43 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 5/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL485783 | 0.97 | MRGPRX4 (0.47) | MRGPRX4MEN1ALDH1A1KMT2AGCGR | |
| Formic Acid SCHEMBL27693269 | 0.90 | MRGPRX4 (0.54) | MRGPRX4MEN1ALDH1A1KMT2ASGMS2 | |
| Formic Acid SCHEMBL27693247 | 0.89 | CNR1 (0.52) | MEN1ALDH1A1KMT2ASGMS2CNR2 | |
| Formic Acid SCHEMBL27712967 | 0.89 | KMT2A (0.55) | MRGPRX4MEN1ALDH1A1KMT2ASGMS2 | |
| Formic Acid SCHEMBL27693432 | 0.88 | CXCR2 (0.46) | MEN1ALDH1A1KMT2ASGMS2CHRM1 | |
| Formic Acid SCHEMBL27693212 | 0.88 | CXCR2 (0.50) | MRGPRX4MEN1ALDH1A1KMT2ASGMS2 | |
| SCHEMBL486088 | 0.87 | MRGPRX4 (0.56) | MRGPRX4MEN1ALDH1A1KMT2ASGMS2 | |
| SCHEMBL485710 | 0.85 | MRGPRX4 (0.56) | MRGPRX4MEN1ALDH1A1KMT2ASGMS2 | |
| SCHEMBL485455 | 0.84 | CXCR2 (0.49) | MEN1ALDH1A1KMT2ASGMS2CHRM1 | |
| SCHEMBL486231 | 0.83 | CXCR2 (0.52) | MRGPRX4MEN1ALDH1A1KMT2ASGMS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094830-A | Fused bicyclic carboxamide derivatives for use as CXCR2 inhibitors in the treatment of inflammation | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-12-26 | — | — | CN | claimed |
| CN-101094830-A | Fused bicyclic carboxamide derivatives for use as CXCR2 inhibitors in the treatment of inflammation | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-12-26 | — | — | CN | disclosed |