Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 10/20 | 0.44 |
| ▸ | CNR1 | P21554 | 10/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL27693212 | 0.96 | CXCR2 (0.50) | CXCR2KMT2AMEN1ALDH1A1SGMS2 | |
| SCHEMBL485710 | 0.88 | MRGPRX4 (0.56) | CXCR2KMT2AMEN1ALDH1A1SGMS2 | |
| SCHEMBL485837 | 0.86 | ALDH1A1 (0.48) | CXCR2KMT2AMEN1ALDH1A1SGMS2 | |
| SCHEMBL486088 | 0.86 | MRGPRX4 (0.56) | CXCR2KMT2AMEN1ALDH1A1SGMS2 | |
| SCHEMBL485783 | 0.85 | MRGPRX4 (0.47) | KMT2AMEN1ALDH1A1SGMS2MRGPRX4 | |
| SCHEMBL485894 | 0.84 | CXCR2 (0.48) | CXCR2KMT2AMEN1ALDH1A1SGMS2 | |
| Formic Acid SCHEMBL27693269 | 0.84 | MRGPRX4 (0.54) | CXCR2KMT2AMEN1ALDH1A1SGMS2 | |
| SCHEMBL485840 | 0.83 | MRGPRX4 (0.47) | KMT2AMEN1ALDH1A1SGMS2MRGPRX4 | |
| Formic Acid SCHEMBL27693239 | 0.83 | CXCR2 (0.47) | CXCR2KMT2AMEN1ALDH1A1SGMS2 | |
| Formic Acid SCHEMBL27693231 | 0.83 | MRGPRX4 (0.45) | KMT2AMEN1ALDH1A1SGMS2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836158-B1 | FUSED BICYCLIC CARBOXAMIDE DERIVATIVES FOR USE AS CXCR2 INHIBITORS IN THE TREATMENT OF INFLAMMATION | SANOFI AVENTIS DEUTSCHLAND (DE) | 2012-02-01 | — | — | EP | claimed |