Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFSF11 | O14788 | 1/20 | 0.53 |
| ▸ | TNF | P01375 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.52 |
| ▸ | GABRD | O14764 | 1/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.52 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.52 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.52 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.52 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.52 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.52 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.52 |
| ▸ | GABRE | P78334 | 1/20 | 0.52 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.52 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.52 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.52 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL615804 | 0.81 | NR4A2 (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28265772 | 0.79 | GABRP (0.53) | TNFSF11TNFGABRPGABRDGABRA1 | |
| SCHEMBL1005283 | 0.78 | GABRP (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5213756 | 0.77 | NQO2 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2841773 | 0.77 | GABRP (0.62) | TNFSF11TNFGABRPGABRDGABRA1 | |
| SCHEMBL15712665 | 0.75 | GABRP (0.61) | TNFSF11TNFGABRPGABRDGABRA1 | |
| SCHEMBL28969553 | 0.74 | GABRP (0.50) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18425322 | 0.74 | GABRP (0.56) | TNFSF11TNFGABRPGABRDGABRA1 | |
| SCHEMBL3624516 | 0.74 | GABRP (0.56) | TNFSF11TNFGABRPGABRDGABRA1 | |
| SCHEMBL28363236 | 0.74 | GABRP (0.63) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101104601-B | Method for preparing zafirlukast important intermediate | HAINAN SHENGKE LIFE SCIENT RES INST | 2011-01-26 | — | — | CN | disclosed |
| CN-101104601-A | Method for preparing zafirlukast important intermediate | HAINAN SHENGKE LIFE SCIENT RES (CN) | 2008-01-16 | — | — | CN | disclosed |