Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CTPS1 | P17812 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5220723 | 0.88 | SMN1; SMN2 (0.45) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5215989 | 0.84 | MAPT (0.63) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5219334 | 0.82 | MEN1 (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5219298 | 0.82 | MAPT (0.50) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5220900 | 0.79 | MAPT (0.54) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5222457 | 0.79 | RAB9A (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5219021 | 0.78 | MAPT (0.42) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5215826 | 0.78 | MAPT (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5220598 | 0.77 | HSD17B10 (0.50) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5217930 | 0.77 | KCNJ6 (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | claimed |
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | disclosed |