Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694795 | 0.90 | MAPT (0.46) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5215588 | 0.87 | MAPT (0.52) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27714640 | 0.86 | MAPT (0.43) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27714642 | 0.84 | MAPT (0.48) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27714646 | 0.83 | MAPT (0.41) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27714644 | 0.82 | MAPT (0.45) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27714641 | 0.79 | MAPT (0.44) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27694723 | 0.79 | MAPT (0.44) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL27714645 | 0.78 | MAPT (0.43) | MAPTLMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5219606 | 0.77 | MAPT (0.44) | MAPTLMNASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | claimed |
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | disclosed |