Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714645 | 0.99 | MAPT (0.43) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27694723 | 0.98 | MAPT (0.44) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5218752 | 0.87 | MAPT (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5221522 | 0.86 | MAPT (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27694721 | 0.86 | NOD1 (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL5218200 | 0.85 | MAPT (0.48) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27714644 | 0.81 | MAPT (0.45) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27694795 | 0.81 | MAPT (0.46) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27694822 | 0.79 | MAPT (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL27714640 | 0.78 | MAPT (0.43) | MAPTSMN1; SMN2LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | claimed |
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | disclosed |