Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28471616 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL1097671 | 0.70 | CYP2A6 (0.42) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL2012336 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL4079696 | 0.70 | CYP2A6 (0.42) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL2008998 | 0.70 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL1605255 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL4897405 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL286416 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL21179481 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR | |
| SCHEMBL2488251 | 0.70 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TDP1CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377847-B | Heterocyclic compound, composition comprising same, and organic light-emitting device comprising same | 三星电子株式会社 | 2024-07-16 | — | — | CN | disclosed |
| CN-117024330-A | Heterocyclic compound, composition comprising same, and organic light-emitting device comprising same | 三星电子株式会社 | 2023-11-10 | — | — | CN | disclosed |
| US-11174272-B2 | 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-11-16 | — | — | US | disclosed |
| US-20210206781-A1 | 1-ARYLCARBONYL-4-OXY-PIPERIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2021-07-08 | — | — | US | disclosed |
| US-10717748-B2 | 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-07-21 | — | — | US | disclosed |
| CN-111384300-A | Organic light emitting device and apparatus including the same | 三星电子株式会社 | 2020-07-07 | — | — | CN | disclosed |
| US-20200157117-A1 | 1-ARYLCARBONYL-4-OXY-PIPERIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2020-05-21 | — | — | US | disclosed |
| US-10550129-B2 | 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2020-02-04 | — | — | US | disclosed |
| EP-2982666-B1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-07 | — | — | EP | disclosed |
| US-20190233436-A1 | 1-ARYLCARBONYL-4-OXY-PIPERIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2019-08-01 | — | — | US | disclosed |
| US-6632543-B1 | Having m-terphenyl group; heat resistanct; bright; long life | IDEMITSU KOSAN CO., LTD. (JP) | 2003-10-14 | — | — | US | disclosed |
| EP-1136469-A1 | AMINE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING THE SAME | Idemitsu Kosan Co., Ltd. (JP) | 2001-09-26 | — | — | EP | disclosed |
| EP-0678505-B1 | Oximethers and fungicides containing them | BASF AG (DE) | 1997-06-04 | — | — | EP | disclosed |
| EP-0483851-B1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | MITSUBISHI CHEM CORP (JP) | 1996-03-13 | — | — | EP | disclosed |
| EP-0679636-A1 | Oximethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1995-11-02 | — | — | EP | disclosed |
| EP-0678505-A1 | Oximethers and fungicides containing them | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-25 | — | — | EP | disclosed |
| US-5446067-A | For treatment of crops, seeds, soils | BASF AKTIENGESELLSCHAFT (DE) | 1995-08-29 | — | — | US | disclosed |
| EP-0498188-A2 | Oximethers and fungicides containing them | BASF Aktiengesellschaft (DE) | 1992-08-12 | — | — | EP | disclosed |
| US-5128350-A | PYRAZOLYL ACRYLIC ACID DERIVATIVES AND AGRICULTURAL/HORTICULTURAL FUNGICIDES CONTAINING SAID DERIVATIVES | MITSUBISHI KASEI CORPORATION (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0483851-A1 | Pyrazolyl acrylic acid derivatives, intermediates thereto, and agricultural/horticultural fungicides containing said derivatives | Mitsubishi Chemical Corporation (JP) | 1992-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157117-A1 | 1-ARYLCARBONYL-4-OXY-PIPERIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PSEN1 | ALDH1A1 101/4885HSD17B10 2762/4885TDP1 250/4885 |
| US-20190233436-A1 | 1-ARYLCARBONYL-4-OXY-PIPERIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PSEN1 | ALDH1A1 101/4885HSD17B10 2762/4885TDP1 250/4885 |
| US-11174272-B2 | 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases | SNCA, HTT, PSEN1 | ALDH1A1 101/4885HSD17B10 2762/4885TDP1 250/4885 |
| US-10717748-B2 | 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases | SNCA, HTT, PSEN1 | ALDH1A1 101/4885HSD17B10 2762/4885TDP1 250/4885 |
| US-10550129-B2 | 1-arylcarbonyl-4-oxy-piperidine compounds useful for the treatment of neurodegenerative diseases | SNCA, HTT, PSEN1 | ALDH1A1 101/4885HSD17B10 2762/4885TDP1 250/4885 |
| US-20210206781-A1 | 1-ARYLCARBONYL-4-OXY-PIPERIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | SNCA, HTT, PSEN1 | ALDH1A1 101/4885HSD17B10 2762/4885TDP1 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.