Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | INPPL1 | O15357 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3737738 | 0.83 | KDM4E (0.43) | KDM4ESMN1; SMN2INPPL1TP53NQO1 | |
| SCHEMBL30926069 | 0.78 | KDM4E (0.56) | KDM4ETP53NQO1HSD17B10MAPT | |
| SCHEMBL5519840 | 0.78 | KDM4E (0.56) | KDM4ETP53NQO1HSD17B10MAPT | |
| SCHEMBL1697477 | 0.75 | KDM4E (0.49) | KDM4ESMN1; SMN2NQO1MAPTMEN1 | |
| SCHEMBL3729905 | 0.74 | KDM4E (0.49) | KDM4ESMN1; SMN2TP53NQO1PLK1 | |
| SCHEMBL3743024 | 0.73 | THRA (0.41) | KDM4ESMN1; SMN2TP53NQO1PLK1 | |
| SCHEMBL4681515 | 0.71 | KDM4E (0.45) | KDM4ETP53NQO1HSD17B10MAPT | |
| SCHEMBL3737734 | 0.71 | PTPN1 (0.50) | KDM4EKMT2A | |
| SCHEMBL9425356 | 0.70 | NQO1 (0.56) | KDM4ETP53NQO1HSD17B10MAPT | |
| SCHEMBL28074624 | 0.70 | HPGD (0.41) | KDM4ESMN1; SMN2CYP2C19INPPL1INPP5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101094677-A | Protein tyrosine phosphatase inhibitors and methods of use thereof | CEPTYR INC (US) | 2007-12-26 | — | — | CN | disclosed |