Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
| ▸ | FNTB | P49356 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208716 | 0.96 | GPR84 (0.60) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL19912238 | 0.96 | GPR84 (0.60) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL28959802 | 0.96 | GPR84 (0.60) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL2376184 | 0.94 | GPR84 (0.64) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL12922833 | 0.94 | GPR84 (0.64) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL3505305 | 0.94 | GPR84 (0.64) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL7064050 | 0.94 | GPR84 (0.64) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL21114449 | 0.94 | GPR84 (0.64) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL7033618 | 0.94 | GPR84 (0.64) | GPR84FFAR1FFAR4CAMK2AALDH1A1 | |
| SCHEMBL6397493 | 0.94 | GPR84 (0.64) | GPR84FFAR1FFAR4CAMK2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114228086-B | Method for preparing high-performance PLA/PBSA miniature product based on miniature injection molding process | 四川大学 | 2022-11-22 | — | — | CN | claimed |
| CN-110681683-A | Complexing agent microcapsule for phytoremediation soil and preparation method thereof | 太仓该亚机器人科技有限公司 | 2020-01-14 | — | — | CN | claimed |
| CN-101073318-A | Pesticide microcapsule | PHYSICAL CHEMISTRY TECHNOLOGY (CN) | 2007-11-21 | — | — | CN | claimed |
| CN-114228086-B | Method for preparing high-performance PLA/PBSA miniature product based on miniature injection molding process | 四川大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-114228086-A | Method for preparing high-performance PLA/PBSA miniature product based on miniature injection molding process | 四川大学 | 2022-03-25 | — | — | CN | disclosed |
| CN-110681683-A | Complexing agent microcapsule for phytoremediation soil and preparation method thereof | 太仓该亚机器人科技有限公司 | 2020-01-14 | — | — | CN | disclosed |
| CN-101073318-A | Pesticide microcapsule | PHYSICAL CHEMISTRY TECHNOLOGY (CN) | 2007-11-21 | — | — | CN | disclosed |