Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL9985763 | 0.91 | CES1 (0.52) | FAAHSOAT1TP53MEN1KMT2A | |
| Formamide SCHEMBL4240947 | 0.86 | FAAH (0.65) | FAAHSOAT1TP53MEN1KMT2A | |
| Formamide SCHEMBL9804248 | 0.84 | SOAT1 (0.69) | FAAHSOAT1TP53MEN1KMT2A | |
| SCHEMBL20284 | 0.83 | — | — | |
| SCHEMBL28855277 | 0.83 | CES1 (0.61) | FAAHSOAT1TP53MEN1KMT2A | |
| Palmitamide SCHEMBL3984610 | 0.81 | SOAT1 (0.65) | FAAHSOAT1TP53MEN1KMT2A | |
| Cyclohexane SCHEMBL3839638 | 0.81 | SOAT1 (0.65) | FAAHSOAT1TP53MEN1KMT2A | |
| Cyclohexane SCHEMBL22283339 | 0.81 | SOAT1 (0.65) | FAAHSOAT1TP53MEN1KMT2A | |
| Cyclohexane SCHEMBL3840067 | 0.81 | SOAT1 (0.65) | FAAHSOAT1TP53MEN1KMT2A | |
| Cyclohexane SCHEMBL2898947 | 0.81 | SOAT1 (0.65) | FAAHSOAT1TP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101155803-A | Method for obtaining a pharmaceutically active compound (irbesartan) and its synthesis intermediate | INKE SA (ES) | 2008-04-02 | — | — | CN | claimed |
| CN-101155803-A | Method for obtaining a pharmaceutically active compound (irbesartan) and its synthesis intermediate | INKE SA (ES) | 2008-04-02 | — | — | CN | disclosed |