Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4615106 | 0.89 | DRD2 (0.53) | DRD2PTGIRADRA1ASIGMAR1ACKR3 | |
| SCHEMBL27698200 | 0.84 | DRD2 (0.42) | DRD2PTGIRADRA1ASIGMAR1ACKR3 | |
| SCHEMBL4617776 | 0.79 | DRD2 (0.51) | DRD2ADRA1AACKR3SMN1; SMN2DRD4 | |
| SCHEMBL4617135 | 0.78 | DRD2 (0.69) | DRD2ADRA1A | |
| SCHEMBL4615785 | 0.77 | DRD2 (0.58) | DRD2ADRA1ASIGMAR1SMN1; SMN2DRD4 | |
| SCHEMBL4617356 | 0.74 | DRD2 (0.51) | DRD2PTGIRADRA1ASMN1; SMN2FAAH | |
| SCHEMBL4617355 | 0.74 | HSP90AA1 (0.52) | DRD2PTGIRADRA1AACKR3SMN1; SMN2 | |
| SCHEMBL4617018 | 0.74 | DRD2 (0.48) | DRD2PTGIRADRA1ASIGMAR1ACKR3 | |
| SCHEMBL4617015 | 0.74 | DRD2 (0.48) | DRD2PTGIRADRA1ASIGMAR1ACKR3 | |
| SCHEMBL4615443 | 0.73 | DRD2 (0.50) | DRD2PTGIRADRA1ASIGMAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048161-A | Arylthiobenzylpiperidine Derivatives | LUNDBECK & CO AS H (DK) | 2007-10-03 | — | — | CN | disclosed |