Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 10/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 2/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395473 | 0.84 | KDM4E (0.44) | MEN1MAPTKMT2AUSP2ALDH1A1 | |
| SCHEMBL3391190 | 0.83 | IKBKB (0.41) | IKBKBMEN1MAPTKMT2AUSP2 | |
| SCHEMBL3395534 | 0.83 | IKBKB (0.48) | IKBKBMEN1MAPTKMT2AUSP2 | |
| Hydrochloric Acid SCHEMBL3395405 | 0.82 | IKBKB (0.41) | IKBKBMEN1MAPTKMT2AUSP2 | |
| SCHEMBL3989890 | 0.82 | TLR9 (0.39) | IKBKBMEN1MAPTKMT2AUSP2 | |
| SCHEMBL3395461 | 0.81 | SCD5 (0.33) | — | |
| SCHEMBL27698208 | 0.79 | RPS6KB1 (0.40) | IKBKBBTKCHUK | |
| SCHEMBL31404482 | 0.79 | HCAR2 (0.39) | IKBKBMEN1MAPTKMT2AUSP2 | |
| SCHEMBL27679141 | 0.79 | CDK2 (0.38) | IKBKBBTKCHUK | |
| SCHEMBL27713739 | 0.78 | IKBKB (0.52) | IKBKBBTKCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101005836-A | Novel indazole carboxamides and their use | SMITHKLINE BEECHAM CORP (US) | 2007-07-25 | — | — | CN | disclosed |