Guanidine

Guanidine

SCHEMBL27698341

CC=CO.N=C(N)N

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2

The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708 0.78
SCHEMBL179822 0.78
SCHEMBL80932 0.78
Urea SCHEMBL332371 0.77
Urea SCHEMBL245716 0.77
Guanidine SCHEMBL8532690 0.75
SCHEMBL15756084 0.74
Ammonia Solution, Strong SCHEMBL8571909 0.74
Guanidine SCHEMBL29138502 0.72
Guanidine SCHEMBL11056748 0.72 ALDH1A1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101095653-B Hair care cleansing formulations with especially dry hair feel BEIERSDORF AG 2012-03-28 CN disclosed
CN-101095652-B Hair care shampoo for increasing color brightness and color freshness of dyed keratin fibers BEIERSDORF AG 2011-04-06 CN disclosed
CN-101095652-A Hair care shampoo for increasing color brightness and color freshness of dyed keratin fibers BEIERSDORF AG (DE) 2008-01-02 CN disclosed
CN-101095653-A Hair care cleansing formulations with especially dry hair feel BEIERSDORF AG (DE) 2008-01-02 CN disclosed