SCHEMBL27698671

SCHEMBL27698671

CCCO[Si](CCC1CO1)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.35
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28615890 0.90 SMN1; SMN2 (0.44) ALDH1A1SMN1; SMN2TDP1
SCHEMBL29175247 0.88 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2TDP1
SCHEMBL28264255 0.87 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2TDP1
SCHEMBL27256450 0.86 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1
SCHEMBL27793109 0.83 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TDP1
SCHEMBL383060 0.82 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1
SCHEMBL28940092 0.82 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2TDP1
SCHEMBL28396883 0.81 SMN1; SMN2 (0.37) ALDH1A1SMN1; SMN2TDP1
SCHEMBL28408372 0.81 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2TDP1
SCHEMBL28954820 0.81 ALDH1A1 (0.47) ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115485345-A Aqueous coating composition and method for preparing same 陶氏环球技术有限责任公司 2022-12-16 CN disclosed
CN-103168080-A Curable composition CEMEDINE CO LTD 2013-06-19 CN disclosed
CN-101151328-B Hot-melt silicone adhesive DOW CORNING TORAY CO LTD 2011-03-30 CN disclosed
CN-101151328-A Hot-melt silicone adhesive DOW CORNING TORAY CO LTD (JP) 2008-03-26 CN disclosed