SCHEMBL27699092

SCHEMBL27699092

Cc1ccccc1OC(Cl)C(=O)Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.43
TSHR P16473 3/20 0.41
NOTUM Q6P988 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP1A2 P05177 4/20 0.39
KDM4E B2RXH2 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
RXRG P48443 1/20 0.38
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
CYP3A4 P08684 3/20 0.37
CYP2D6 P10635 3/20 0.37
CHRM1 P11229 2/20 0.37
ADRA2B P18089 2/20 0.37
SLC6A2 P23975 2/20 0.37
HTR2A P28223 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5053387 0.85 KMT2A (0.43) HPGDTSHRNOTUMTDP1ATM
SCHEMBL29249525 0.82 HPGD (0.44) HPGDTSHRNOTUMTDP1ATM
SCHEMBL2058985 0.81 HPGD (0.54) HPGDTSHRNOTUMTDP1ATM
SCHEMBL28112030 0.81 KMT2A (0.56) TSHRATMCYP1A2KDM4ESMN1; SMN2
SCHEMBL11841962 0.81 TSHR (0.42) HPGDTSHRNOTUMTDP1ATM
SCHEMBL29249526 0.81 TDP1 (0.54) HPGDTSHRTDP1ATML3MBTL1
SCHEMBL28175837 0.79 ALDH1A1 (0.45) HPGDSMN1; SMN2RXRARXRBKMT2A
SCHEMBL28257658 0.77 ALDH1A1 (0.46) HPGDTSHRNOTUMTDP1ATM
SCHEMBL31121337 0.76 TSHR (0.43) HPGDTSHRL3MBTL1CYP1A2KDM4E
SCHEMBL10458585 0.76 CYP1A2 (0.51) HPGDTSHRTDP1ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101052459-B Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and method for water treatment using the same TORAY INDUSTRIES 2012-04-04 CN claimed
CN-101052459-A Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and method for water treatment using the same TORAY INDUSTRIES (JP) 2007-10-10 CN claimed
CN-110483423-A P2X4 receptor antagonist NIPPON CHEMIPHAR CO 2019-11-22 CN disclosed
CN-108863959-A P2X4 RECEPTOR ANTAGONIST 日本化学药品株式会社 2018-11-23 CN disclosed
CN-101052459-B Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and method for water treatment using the same TORAY INDUSTRIES 2012-04-04 CN disclosed
CN-101056695-B Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and treatment method for boron-containing water using the same TORAY INDUSTRIES 2011-01-26 CN disclosed
CN-101056695-A Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and treatment method for boron-containing water using the same TORAY INDUSTRIES (JP) 2007-10-17 CN disclosed
CN-101052459-A Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and method for water treatment using the same TORAY INDUSTRIES (JP) 2007-10-10 CN disclosed