Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.36 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.35 |
| ▸ | GAPDH | P04406 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.35 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297374 | 0.86 | HIF1A (0.65) | HIF1AADORA1HSPA5HSPA8RXFP1 | |
| SCHEMBL17490198 | 0.82 | HIF1A (0.48) | HIF1AADORA1HSPA5ADORA3 | |
| SCHEMBL867517 | 0.76 | PI4KA (0.50) | HIF1AADORA1HSPA5HSPA8RXFP1 | |
| SCHEMBL24591605 | 0.75 | HIF1A (0.52) | HIF1AADORA1HSPA5HSPA8ADORA3 | |
| SCHEMBL264903 | 0.74 | ADORA2A (0.47) | HIF1AADORA1HSPA5HSPA8RXFP1 | |
| SCHEMBL264540 | 0.74 | ADORA2A (0.47) | HIF1AADORA1HSPA5HSPA8RXFP1 | |
| SCHEMBL866882 | 0.74 | ATG7 (0.48) | HIF1A | |
| SCHEMBL866573 | 0.74 | ATG7 (0.48) | HIF1A | |
| SCHEMBL11997788 | 0.73 | HIF1A (0.47) | HIF1AADORA1HSPA5HSPA8RXFP1 | |
| SCHEMBL10149306 | 0.72 | HIF1A (0.46) | HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166750-A | Furanopyrimidine compounds and thienopyrimidine compounds for therapy | BIOCRYST PHARM INC (US) | 2008-04-23 | — | — | CN | claimed |
| CN-101166750-A | Furanopyrimidine compounds and thienopyrimidine compounds for therapy | BIOCRYST PHARM INC (US) | 2008-04-23 | — | — | CN | disclosed |