Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | HBB | P68871 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL28052716 | 0.96 | ALDH1A1 (0.50) | ALDH1A1TDP1MEN1KMT2ACA5A | |
| Ethylene Glycol SCHEMBL7909184 | 0.92 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ACA5A | |
| Ethylene Glycol SCHEMBL28323165 | 0.92 | — | — | |
| Ethylene Glycol SCHEMBL28274699 | 0.92 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ACA5A | |
| Ethylene Glycol SCHEMBL9462278 | 0.92 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ACA5A | |
| Ethylene Glycol SCHEMBL28898891 | 0.92 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ACA5A | |
| Ethylene Glycol SCHEMBL19741998 | 0.92 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ACA5A | |
| Ethylene Glycol SCHEMBL563825 | 0.92 | — | — | |
| Ethylene Glycol SCHEMBL8045241 | 0.92 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ACA5A | |
| Ethylene Glycol SCHEMBL27611334 | 0.92 | ALDH1A1 (0.53) | ALDH1A1TDP1MEN1KMT2ACA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777098-B | Method for preparing two-dimensional bismuth oxide nanosheet | 中国科学院大学温州研究院(温州生物材料与工程研究所) | 2022-11-11 | — | — | CN | claimed |
| CN-113041992-B | Halloysite-based efficient adsorbent for removing radioactive I-and preparation method thereof | 中国科学院地球化学研究所 | 2022-07-26 | — | — | CN | claimed |
| CN-113041992-A | Halloysite-based efficient adsorbent for removing radioactive I-and preparation method thereof | 中国科学院地球化学研究所 | 2021-06-29 | — | — | CN | claimed |
| CN-109706477-B | Preparation of BiVO by using solvothermal method to generate intermediate4Method for producing thin film and use thereof | 福州大学 | 2021-04-27 | — | — | CN | claimed |
| CN-110639563-B | Bismuth oxychloride/silver ferrite ternary composite Z-type photocatalyst and preparation method and application thereof | 湖南大学 | 2020-08-21 | — | — | CN | claimed |
| CN-109957814-B | Bi-BiOI/TNA composite material and application thereof | 江西科技学院 | 2020-05-01 | — | — | CN | claimed |
| CN-110639563-A | Bismuth oxychloride/silver ferrite ternary composite Z-type photocatalyst and preparation method and application thereof | 湖南大学 | 2020-01-03 | — | — | CN | claimed |
| CN-109706477-A | One kind generating intermediate with solvent-thermal method and prepares BiVO4The method and its application of film | 福州大学 | 2019-05-03 | — | — | CN | claimed |
| CN-109382127-A | A kind of novel visible catalysis material purified for indoor formaldehyde and benzene | 内蒙古大学 | 2019-02-26 | — | — | CN | claimed |
| CN-109107579-A | It is a kind of can Magneto separate bismuth tungstate composite material preparation method | 中国计量大学 | 2019-01-01 | — | — | CN | claimed |
| CN-109078654-A | PVP modified graphene loads BiOCl photochemical catalyst and preparation method thereof | 沈阳理工大学 | 2018-12-25 | — | — | CN | claimed |
| CN-108686695-A | Graphene oxide/carbonitride/bismuth oxyiodide composite material and preparation method and application | 江苏大学 | 2018-10-23 | — | — | CN | claimed |
| CN-107215896-A | The regulation and control method of monoclinic phase pucherite appearance structure transformation | 辽宁科技大学 | 2017-09-29 | — | — | CN | claimed |
| CN-105460974-B | Defect-rich ultra-thin bismuth oxyiodide nano-sheet preparation method | 南阳师范学院 | 2017-02-22 | — | — | CN | claimed |
| CN-106348383-A | C3N4-Bi2O3-BiOI-TiO2NTs visible-light response photocatalysis electrode as well as preparation method and application thereof | 浙江工商大学 | 2017-01-25 | — | — | CN | claimed |
| CN-105460974-A | Defect-rich ultra-thin bismuth oxyiodide nano-sheet preparation method | UNIV NANYANG NORMAL | 2016-04-06 | — | — | CN | claimed |
| CN-113083287-B | Bismuth and bismuth tungstate composite powder with nano-particle stacking lamellar structure and preparation method thereof | 沈阳工业大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-111747446-B | Method for preparing small-size monodisperse bismuth oxide | 温州医科大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-102531678-A | Processing method for improving electricity property stability of ZnO pressure-sensitive ceramics under direct-current electric field | SHANGHAI INST CERAMICS | 2012-07-04 | — | — | CN | disclosed |
| CN-101024251-A | Method for preparing nano metal | XIBEI POLYTECHNIQUE UNIV (CN) | 2007-08-29 | — | — | CN | disclosed |