Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 4/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27699395 | 1.00 | LTA4H (0.48) | LTA4HACHEBCHEALDH1A1LMNA | |
| SCHEMBL5456925 | 0.90 | LTA4H (0.54) | LTA4HACHEALDH1A1LMNAKMT2A | |
| SCHEMBL5242188 | 0.90 | LTA4H (0.54) | LTA4HACHEALDH1A1LMNAKMT2A | |
| Tert-Butyl Formate SCHEMBL27510238 | 0.88 | LTA4H (0.51) | LTA4HACHEBCHESIGMAR1CYP2C19 | |
| Tert-Butyl Formate SCHEMBL27557426 | 0.81 | LTA4H (0.49) | LTA4HACHEKMT2ASIGMAR1MEN1 | |
| SCHEMBL10674002 | 0.80 | LTA4H (0.54) | LTA4HALDH1A1LMNAKMT2ASIGMAR1 | |
| SCHEMBL25154290 | 0.80 | LTA4H (0.56) | LTA4HALDH1A1LMNAKMT2ASIGMAR1 | |
| SCHEMBL3626359 | 0.80 | LTA4H (0.56) | LTA4HALDH1A1LMNAKMT2ASIGMAR1 | |
| SCHEMBL3493009 | 0.80 | LTA4H (0.56) | LTA4HALDH1A1LMNAKMT2ASIGMAR1 | |
| SCHEMBL691646 | 0.79 | LTA4H (0.54) | LTA4HACHEBCHESCN4ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101048405-A | Aryl-substituted piperazine derivatives | NEUROGEN CORP (US) | 2007-10-03 | — | — | CN | disclosed |