Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | PAK4 | O96013 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699228 | 0.84 | CHEK1 (0.38) | HPGDCHEK1AURKADAPK3JAK2 | |
| SCHEMBL27699256 | 0.80 | CHEK1 (0.40) | HPGDCHEK1AURKADAPK3JAK2 | |
| SCHEMBL27699430 | 0.79 | MAPT (0.37) | HPGDKDM4EMEN1KMT2APOLB | |
| SCHEMBL27699265 | 0.78 | CYP2A6 (0.46) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL11800551 | 0.78 | HPGD (0.49) | HPGDCHEK1AURKADAPK3JAK2 | |
| SCHEMBL2159987 | 0.74 | HTR2A (0.44) | HPGDKDM4EMEN1KMT2APOLB | |
| SCHEMBL27699188 | 0.73 | NPC1 (0.50) | KDM4EMEN1KMT2APOLBLMNA | |
| SCHEMBL11609433 | 0.71 | KMT2A (0.46) | HPGDMMP2MMP9MMP8MMP13 | |
| SCHEMBL3274448 | 0.70 | KDM4E (0.49) | HPGDCHEK1AURKADAPK3JAK2 | |
| SCHEMBL11607700 | 0.70 | MEN1 (0.40) | HPGDMMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166735-A | Novel oxadiazole derivatives and their medical use | NEUROSEARCH AS (DK) | 2008-04-23 | — | — | CN | disclosed |