SCHEMBL27699463

SCHEMBL27699463

CC(=O)OSc1cccnc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
KMT2A Q03164 5/20 0.40
CYP3A4 P08684 3/20 0.40
CYP1A2 P05177 2/20 0.40
APP P05067 1/20 0.40
GAA P10253 1/20 0.40
HCAR3 P49019 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 2/20 0.39
CYP11B1 P15538 1/20 0.39
CYP11B2 P19099 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
F7 P08709 1/20 0.39
F3 P13726 1/20 0.39
SARM1 Q6SZW1 1/20 0.39
SIRT2 Q8IXJ6 1/20 0.39
SIRT6 Q8N6T7 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
SIRT3 Q9NTG7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28198363 0.84 ALDH1A1 (0.46) ALDH1A1KMT2AAPPGAAHCAR3
SCHEMBL6210380 0.79 ALDH1A1 (0.41) ALDH1A1KMT2ACYP3A4CYP1A2GAA
SCHEMBL27346246 0.77 KMT2A (0.41) ALDH1A1KMT2ACYP1A2MEN1LMNA
SCHEMBL5355354 0.77 ALDH1A1 (0.45) ALDH1A1CYP3A4GAALMNATDP1
SCHEMBL6211802 0.76 IDO1 (0.44) ALDH1A1KMT2ACYP3A4CYP1A2GAA
SCHEMBL27699462 0.76 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP1A2APPGAA
SCHEMBL8226111 0.75
SCHEMBL13041722 0.75
Methyl Alcohol SCHEMBL6766122 0.75 ALDH1A1 (0.44) ALDH1A1CYP3A4GAALMNATDP1
SCHEMBL27980658 0.74 ALDH1A1 (0.44) ALDH1A1CYP3A4CYP1A2APPGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101161248-B Novel anti-hepatitis B virus medicine preparing method UNIV LIAONING 2011-05-04 CN disclosed
CN-101161248-A Novel anti-hepatitis B virus medicine and its preparing method UNIV LIAONING (CN) 2008-04-16 CN disclosed