Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951078 | 0.89 | ALDH1A1 (0.36) | TYRTP53TDP1MAPTALDH1A1 | |
| SCHEMBL12802008 | 0.84 | TYR (0.43) | TYRTP53TDP1MEN1CYP3A4 | |
| SCHEMBL29263436 | 0.83 | TYR (0.61) | TYRTP53TDP1MEN1CYP3A4 | |
| SCHEMBL27817833 | 0.83 | TYR (0.43) | TYRTP53TDP1MEN1CYP3A4 | |
| SCHEMBL10381564 | 0.82 | ALDH1A1 (0.39) | TP53TDP1MAPTALDH1A1CHRNB2 | |
| SCHEMBL12802596 | 0.79 | TYR (0.43) | TYRTP53TDP1MEN1CYP3A4 | |
| SCHEMBL809759 | 0.78 | TYR (0.39) | TYRTP53TDP1MEN1CYP3A4 | |
| SCHEMBL10426037 | 0.77 | TYR (0.37) | TYRTP53TDP1MEN1CYP3A4 | |
| SCHEMBL12802075 | 0.77 | TYR (0.46) | TYRTP53TDP1MEN1CYP3A4 | |
| SCHEMBL11410036 | 0.77 | TYR (0.63) | TYRTP53TDP1MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160285-A | Substituted sulfonylaminoarylmethyl cyclopropanecarboxamide as vr1 receptor antagonists | PFIZER (US) | 2008-04-09 | — | — | CN | disclosed |