Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KARS1 | Q15046 | 12/20 | 0.44 |
| ▸ | SYK | P43405 | 4/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2868393 | 1.00 | KARS1 (0.44) | KARS1SYKAAK1PIK3C3 | |
| SCHEMBL2862731 | 0.86 | KARS1 (0.55) | KARS1SYK | |
| SCHEMBL2863845 | 0.84 | KARS1 (0.42) | KARS1SYK | |
| SCHEMBL13136083 | 0.83 | KDR (0.51) | KARS1SYK | |
| SCHEMBL13136030 | 0.77 | KARS1 (0.53) | KARS1SYK | |
| SCHEMBL2859905 | 0.75 | KARS1 (0.55) | KARS1SYK | |
| SCHEMBL13136047 | 0.74 | KARS1 (0.54) | KARS1SYK | |
| SCHEMBL2866084 | 0.74 | SYK (0.52) | KARS1SYK | |
| SCHEMBL2865508 | 0.74 | KARS1 (0.52) | KARS1SYK | |
| SCHEMBL2865504 | 0.74 | KARS1 (0.52) | KARS1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101166734-A | Novel aminopyridine compounds having Syk inhibitory activity | JAPAN TOBACCO INC (JP) | 2008-04-23 | — | — | CN | disclosed |