Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052379 | 0.84 | TDP1 (0.50) | RAB9AMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL5844473 | 0.82 | TDP1 (0.49) | RAB9AMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL21328039 | 0.82 | TDP1 (0.49) | RAB9AMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL21328027 | 0.82 | TDP1 (0.49) | RAB9AMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL21328025 | 0.82 | TDP1 (0.49) | RAB9AMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL3962123 | 0.82 | TDP1 (0.49) | RAB9AMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL21328029 | 0.82 | TDP1 (0.49) | RAB9AMAPTL3MBTL1ALDH1A1HPGD | |
| SCHEMBL8367844 | 0.81 | ALDH1A1 (0.49) | MRGPRX4KDM4EPPARGRAB9AACHE | |
| SCHEMBL27692981 | 0.81 | NPC1 (0.42) | KDM4ERAB9AL3MBTL1NPSR1ALDH1A1 | |
| Dimethylamine SCHEMBL10589958 | 0.79 | TDP1 (0.56) | KDM4EMAPTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103224474-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-31 | — | — | CN | claimed |
| CN-107382699-B | Technique for preparing acrylate by epoxides | 诺沃梅尔公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-103224474-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-31 | — | — | CN | disclosed |
| CN-103214409-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE | 2013-07-24 | — | — | CN | disclosed |
| CN-101027279-A | Synthesis of tetracyclines and analogues thereof | HARVARD COLLEGE (US) | 2007-08-29 | — | — | CN | disclosed |