Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 13/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.59 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.59 |
| ▸ | PGR | P06401 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | TNF | P01375 | 1/20 | 0.59 |
| ▸ | IL6 | P05231 | 1/20 | 0.59 |
| ▸ | GLUL | P15104 | 1/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27748218 | 0.94 | HIF1A (0.61) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL7142740 | 0.94 | HIF1A (0.60) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL7145318 | 0.94 | HIF1A (0.60) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL28286516 | 0.94 | HIF1A (0.60) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL7613028 | 0.94 | HIF1A (0.60) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL7986 | 0.93 | HIF1A (0.60) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL677626 | 0.93 | HIF1A (0.61) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL945988 | 0.93 | HIF1A (0.65) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL22042713 | 0.92 | HIF1A (0.59) | HIF1AHSD17B10NR3C1NR3C2PGR | |
| SCHEMBL264554 | 0.92 | HIF1A (0.64) | HIF1AHSD17B10NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101796039-B | Phenylacetic acid compound | ONO PHARMACEUTICAL CO | 2012-09-19 | — | — | CN | disclosed |
| CN-101796039-A | Phenylacetic acid compound | ONO PHARMACEUTICAL CO | 2010-08-04 | — | — | CN | disclosed |
| CN-101759628-A | Ethynylindole compounds | ONO PHARMACEUTICAL CO | 2010-06-30 | — | — | CN | disclosed |
| CN-101534862-A | External preparation for skin | ROHTO PHARMA (JP) | 2009-09-16 | — | — | CN | disclosed |
| CN-101443322-A | Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-101340916-A | Preparation for external use having improved temporal stability of steroid | KOWA CO (JP) | 2009-01-07 | — | — | CN | disclosed |
| CN-101115709-A | Aminocarboxylic acid derivative and medical use thereof | ONO PHARMACEUTICAL CO (JP) | 2008-01-30 | — | — | CN | disclosed |
| CN-101094662-A | Hydrous adhesive patch | KOWA CO (JP) | 2007-12-26 | — | — | CN | disclosed |
| CN-101056855-A | Nitrogen-containing heterocyclic derivative and drug containing same as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2007-10-17 | — | — | CN | disclosed |