Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.78 |
| ▸ | APAF1 | O14727 | 2/20 | 0.52 |
| ▸ | TDP2 | O95551 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149579 | 0.88 | DHODH (0.61) | DHODHAPAF1TDP2MAPTALDH1A1 | |
| SCHEMBL5821364 | 0.85 | APAF1 (0.65) | DHODHAPAF1TDP2MAPTALDH1A1 | |
| SCHEMBL9713924 | 0.81 | APAF1 (0.56) | DHODHAPAF1TDP2MAPTALDH1A1 | |
| SCHEMBL5806521 | 0.81 | APAF1 (0.56) | DHODHAPAF1TDP2MAPTALDH1A1 | |
| SCHEMBL571484 | 0.80 | DHODH (0.60) | DHODHAPAF1MAPTALDH1A1RAB9A | |
| SCHEMBL14027541 | 0.79 | DHODH (0.51) | DHODHAPAF1TDP2MAPTALDH1A1 | |
| SCHEMBL972010 | 0.78 | MAPT (0.62) | DHODHAPAF1TDP2MAPTALDH1A1 | |
| SCHEMBL8143790 | 0.77 | APAF1 (0.50) | DHODHAPAF1TDP2MAPTALDH1A1 | |
| SCHEMBL8461456 | 0.77 | APAF1 (0.50) | DHODHAPAF1TDP2MAPTALDH1A1 | |
| SCHEMBL8781044 | 0.77 | APAF1 (0.60) | DHODHAPAF1TDP2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180379-B | Dihydroxy enol compounds used in chemical mechanical polishing compositions having metal ion oxidizers | AIR PROD & CHEM | 2013-07-24 | — | — | CN | disclosed |
| CN-101180379-A | Dihydroxy enol compounds used in chemical mechanical polishing compositions having metal ion oxidizers | DUPONT AIR PROD NANOMATERIALS (US) | 2008-05-14 | — | — | CN | disclosed |