Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27838771 | 0.82 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27721658 | 0.82 | TDP1 (0.38) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27701029 | 0.81 | TDP1 (0.37) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27721654 | 0.79 | PNMT (0.47) | TDP1 | |
| SCHEMBL3881522 | 0.79 | PNMT (0.36) | — | |
| Tert-Butyl Formate SCHEMBL27721659 | 0.78 | TDP1 (0.34) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27701309 | 0.76 | TDP1 (0.41) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27773262 | 0.74 | TDP1 (0.50) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27721637 | 0.73 | PNMT (0.47) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27811317 | 0.73 | TDP1 (0.41) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101119968-B | Heterocyclically substituted phenyl methanone derivatives as glycine transporter 1 inhibitors | HOFFMANN LA ROCHE | 2011-08-31 | — | — | CN | disclosed |
| CN-101119968-A | Heterocyclically substituted phenyl methanone derivatives as glycine transporter 1 inhibitors | HOFFMANN LA ROCHE (CH) | 2008-02-06 | — | — | CN | disclosed |