SCHEMBL2770110

SCHEMBL2770110

N=C(N)NCCCC(NC(=O)C1CCCN1C(=O)C(N)Cc1ccccc1)C(=O)O.O=C(CCl)CCl

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.54
▸ OPRM1 P35372 7/20 0.52
▸ OPRD1 P41143 4/20 0.51
▸ OPRK1 P41145 2/20 0.51
▸ NPFFR1 Q9GZQ6 2/20 0.48
▸ NPFFR2 Q9Y5X5 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19520657 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL9314374 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL1239590 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL342640 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL20502714 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL6497247 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL2119635 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL2778546 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL6850160 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL2778544 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1853104-B Protocol and apparatus for determining heparin-induced thrombocytopenia HAEMOSCOPE CORP 2013-04-10 — — CN claimed
CN-114295821-A Indoor quality assessment sample of thrombus elastogram experimental reagent and preparation method and application thereof 深圳麦科田生物医疗技术股份有限公司 2022-04-08 — — CN disclosed
CN-110514851-A The detection method and detection kit of blood platelet inhibiting rate MEDCAPTAIN MEDICAL TECH CO LTD 2019-11-29 — — CN disclosed
CN-1853104-B Protocol and apparatus for determining heparin-induced thrombocytopenia HAEMOSCOPE CORP 2013-04-10 — — CN disclosed
US-7811792-B2 using a hemostasis analyzer is to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis parameters CORA HEALTHCARE, INC. (US) 2010-10-12 — — US disclosed
EP-1649292-B1 PROTOCOL FOR DETERMINING HEPARIN-INDUCED THROMBOCYTOPENIA CORA HEALTHCARE INC (US) 2010-04-21 — — EP disclosed
US-20090208988-A1 Protocol and Apparatus for Determining Heparin-induced Thrombocytopenia CORA HEALTCARE, INC. (US) 2009-08-20 — — US disclosed
US-7524670-B2 Protocol and apparatus for determining heparin-induced thrombocytopenia HAEMOSCOPE CORPORATION (US) 2009-04-28 — — US disclosed
CN-1853104-A Protocol and apparatus for determining heparin-induced thrombocytopenia HAEMOSCOPE CORP (US) 2006-10-25 — — CN disclosed
EP-1649292-A1 PROTOCOL AND APPARATUS FOR DETERMINING HEPARIN-INDUCED THROMBOCYTOPENIA Haemoscope Corporation (US) 2006-04-26 — — EP disclosed
WO-2005017534-A1 PROTOCOL AND APPARATUS FOR DETERMINING HEPARIN-INDUCED THROMBOCYTOPENIA HAEMOSCOPE CORPORATION (US) 2005-02-24 — — WO disclosed
US-20050032142-A1 Protocol and apparatus for determining heparin-induced thrombocytopenia HAEMONETICS CORPORATION 2005-02-10 — — US disclosed
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