SCHEMBL342640

SCHEMBL342640

N=C(N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](N)Cc1ccccc1)C(=O)O.O=C(CCl)CCl

nearest known ligand 0.54

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.54
▸ OPRM1 P35372 7/20 0.52
▸ OPRD1 P41143 4/20 0.51
▸ OPRK1 P41145 2/20 0.51
▸ NPFFR1 Q9GZQ6 2/20 0.48
▸ NPFFR2 Q9Y5X5 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19520657 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL2770110 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL9314374 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL1239590 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL20502714 1.00 F2 (0.54) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL6497247 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL2119635 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL2778546 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL6850160 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1
SCHEMBL2778544 0.96 F2 (0.57) F2OPRM1OPRD1OPRK1NPFFR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250154113-A1 Microcrystalline Diketopiperazine Compositions and Methods WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2025-05-15 — — US claimed
EP-3587404-B1 MICROCRYSTALLINE DIKETOPIPERAZINE COMPOSITIONS, METHODS FOR PREPARATION AND USE THEREOF MANNKIND CORP (US) 2022-07-13 — — EP claimed
US-20220074949-A1 METHODS OF PREPARING SAMPLES FOR PROTEOMIC ANALYSIS STRECK, INC. 2022-03-10 — — US claimed
US-20220048868-A1 Microcrystalline Diketopiperazine Compositions and Methods WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2022-02-17 — — US claimed
US-11192862-B2 Microcrystalline diketopiperazine compositions and methods MANNKIND CORPORATION (US) 2021-12-07 — — US claimed
EP-3903106-A1 METHODS OF PREPARING SAMPLES FOR PROTEOMIC ANALYSIS Streck, Inc. (US) 2021-11-03 — — EP claimed
US-11013692-B2 Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents MANNKIND CORPORATION (US) 2021-05-25 — — US claimed
US-20200339520-A1 Microcrystalline Diketopiperazine Compositions and Methods WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2020-10-29 — — US claimed
US-10745359-B2 Microcrystalline diketopiperazine compositions and methods MANNKIND CORPORATION (US) 2020-08-18 — — US claimed
WO-2020140035-A1 METHODS OF PREPARING SAMPLES FOR PROTEOMIC ANALYSIS STRECK, INC. (US) 2020-07-02 — — WO claimed
EP-2114137-A2 STABILISATION OF BIOLOGICAL CELL MARKERS The University of Nottingham (GB) 2009-11-11 — — EP claimed
WO-2008107724-A2 STABILISATION OF BIOLOGICAL CELL MARKERS THE UNIVERSITY OF NOTTINGHAM (GB) 2008-09-12 — — WO claimed
US-7235377-B2 Determining hemostatic competence of blood by contacting blood sample with an effective amount of tissue factor to coagulate blood, and determinig amount of thrombin in blood sample at a prdetermined time point, where amount of thrombin is indicative of the hemostatic competence THE UNIVERSITY OF VERMONT AND STATE AGRICULTURE COLLEGE (US) 2007-06-26 — — US claimed
EP-1600777-A2 A single-tube method and system for platelet function analysis Helena Laboratories Corporation (US) 2005-11-30 — — EP claimed
US-20050118653-A1 Determining hemostatic competence of blood by contacting blood sample with an effective amount of tissue factor to coagulate blood, and determinig amount of thrombin in blood sample at a prdetermined time point, where amount of thrombin is indicative of the hemostatic competence THE UNIVERSITY OF VERMONT AND STATE AGRICULTURE COLLEGE 2005-06-02 — — US claimed
WO-2005017486-A2 A GLOBAL TEST OF THE HEMOSTATIC SYSTEM MANN KENNETH G (US) 2005-02-24 — — WO claimed
US-20040219682-A1 Single-tube method and system for platelet function analysis HELENA LABORATORIES CORPORATION 2004-11-04 — — US claimed
US-20040219681-A1 Two-tube method and system for platelet function analysis using platelet count HELENA LABORATORIES CORPORATION 2004-11-04 — — US claimed
US-5370660-A Apparatus and method for delivering a vessel plug into the body of a patient CORDIS CORPORATION (US) 1994-12-06 — — US claimed
US-5318524-A Fibrin sealant delivery kit CRYOLIFE, INC. (US) 1994-06-07 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11192862-B2 Microcrystalline diketopiperazine compositions and methods RRP15, DKK1, SPOP F2 4460/4885OPRM1 3137/4885OPRD1 2888/4885
US-20200339520-A1 Microcrystalline Diketopiperazine Compositions and Methods RRP15, DKK1, SPOP F2 4460/4885OPRM1 3137/4885OPRD1 2888/4885
US-20220048868-A1 Microcrystalline Diketopiperazine Compositions and Methods RRP15, DKK1, SPOP F2 4460/4885OPRM1 3137/4885OPRD1 2888/4885
US-20250154113-A1 Microcrystalline Diketopiperazine Compositions and Methods RRP15, DKK1, SPOP F2 4460/4885OPRM1 3137/4885OPRD1 2888/4885
US-10745359-B2 Microcrystalline diketopiperazine compositions and methods RRP15, DKK1, SPOP F2 4460/4885OPRM1 3137/4885OPRD1 2888/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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