Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSS | P25774 | 4/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075224 | 1.00 | CTSK (0.48) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL31085224 | 1.00 | CTSK (0.48) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL3624029 | 0.94 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL3656517 | 0.94 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL19668435 | 0.90 | CTSK (0.49) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL4409723 | 0.90 | CTSK (0.49) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL31072330 | 0.90 | CTSK (0.49) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL6745774 | 0.89 | CTSK (0.56) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL14150791 | 0.89 | CTSK (0.56) | CTSKCTSSHDAC4HDAC1ALDH1A1 | |
| SCHEMBL2074961 | 0.88 | CTSK (0.50) | CTSKCTSSHDAC4HDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101115742-B | Heterocycle derivatives as histone deacetylase (hdac) inhibitors | ANGELETTI P IST RICHERCHE BIO | 2011-06-22 | — | — | CN | disclosed |
| CN-101115742-A | Heterocycle derivatives as histone deacetylase (hdac) inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2008-01-30 | — | — | CN | disclosed |