Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701644 | 0.88 | HDAC1 (0.57) | HDAC1 | |
| SCHEMBL27722213 | 0.83 | HDAC1 (0.52) | HDAC1 | |
| SCHEMBL27701807 | 0.80 | PLAU (0.44) | HDAC1 | |
| SCHEMBL27722214 | 0.78 | HDAC1 (0.39) | HDAC1 | |
| SCHEMBL27722216 | 0.78 | HDAC1 (0.41) | HDAC1 | |
| SCHEMBL27701912 | 0.77 | HDAC1 (0.49) | HDAC1 | |
| SCHEMBL27722200 | 0.77 | HDAC1 (0.41) | HDAC1 | |
| SCHEMBL27722330 | 0.76 | HDAC1 (0.40) | HDAC1 | |
| SCHEMBL27722204 | 0.76 | HDAC1 (0.44) | HDAC1 | |
| SCHEMBL27701631 | 0.74 | HDAC1 (0.42) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163703-B | Imidazo [1,2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG | 2010-12-15 | — | — | CN | disclosed |
| CN-101163703-A | Imidazo [1, 2-A ] pyridine derivatives as Peptide Deformylase (PDF) inhibitors | NOVARTIS AG (CH) | 2008-04-16 | — | — | CN | disclosed |