Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 7/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR2B | P41595 | 1/20 | 0.58 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.58 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | NPY2R | P49146 | 1/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262448 | 0.86 | CYP2C9 (0.63) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL14172993 | 0.84 | SCD (0.59) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL13983799 | 0.84 | SCD (0.62) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL12894564 | 0.84 | SCD (0.59) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL10304326 | 0.84 | CYP2C9 (0.60) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL27701738 | 0.83 | CYP2C9 (0.60) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL2006284 | 0.83 | CYP2C9 (0.59) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL2820604 | 0.82 | SCD (0.58) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL2821970 | 0.82 | MGLL (0.58) | SCDCYP2C9CYP2C19HTR2BMAPK14 | |
| SCHEMBL4716887 | 0.82 | SCD (0.56) | SCDCYP2C9CYP2C19HTR2BMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101083982-A | Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes | XENON PHARMACEUTICALS INC (CA) | 2007-12-05 | — | — | CN | disclosed |