Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ME2 | P23368 | 1/20 | 0.49 |
| ▸ | ME1 | P48163 | 1/20 | 0.49 |
| ▸ | ME3 | Q16798 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21114463 | 0.85 | IDO1 (0.52) | IDO1ALDH1A1HPGDGPR35KDM4E | |
| SCHEMBL9394407 | 0.82 | ALDH1A1 (0.56) | IDO1ALDH1A1HPGDGPR35KDM4E | |
| SCHEMBL9397171 | 0.82 | IDO1 (0.49) | IDO1ALDH1A1HPGDGPR35KDM4E | |
| Ethylene Glycol SCHEMBL27905573 | 0.81 | IDO1 (0.61) | IDO1ALDH1A1HPGDGPR35KDM4E | |
| SCHEMBL29452878 | 0.80 | MEN1 (0.46) | GPR35KDM4ENR4A1L3MBTL1MYC | |
| SCHEMBL21177046 | 0.80 | MEN1 (0.46) | GPR35KDM4ENR4A1L3MBTL1MYC | |
| SCHEMBL29373760 | 0.80 | IDO1 (0.71) | IDO1ALDH1A1HPGDGPR35KDM4E | |
| SCHEMBL69178 | 0.80 | IDO1 (0.71) | IDO1ALDH1A1HPGDGPR35KDM4E | |
| SCHEMBL28324640 | 0.80 | HMGB1 (0.45) | ALDH1A1HPGDHSD17B10L3MBTL1PTPN1 | |
| SCHEMBL28183452 | 0.79 | KDM4E (0.50) | IDO1ALDH1A1HPGDGPR35KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101175720-A | Novel haloalkyl sulfone substituted compounds useful for the treatment of obesity and diabetes | NOVO NORDISK AS (DK) | 2008-05-07 | — | — | CN | claimed |
| CN-101175720-A | Novel haloalkyl sulfone substituted compounds useful for the treatment of obesity and diabetes | NOVO NORDISK AS (DK) | 2008-05-07 | — | — | CN | disclosed |