Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701853 | 1.00 | ATM (0.32) | ATM | |
| SCHEMBL27682574 | 0.81 | ATM (0.30) | ATM | |
| SCHEMBL27682576 | 0.81 | ATM (0.30) | ATM | |
| SCHEMBL28768882 | 0.78 | — | — | |
| SCHEMBL28768883 | 0.78 | — | — | |
| SCHEMBL28014787 | 0.76 | TDP1 (0.45) | — | |
| SCHEMBL28014788 | 0.76 | TDP1 (0.45) | — | |
| SCHEMBL28014790 | 0.74 | TDP1 (0.41) | — | |
| SCHEMBL28014786 | 0.74 | TDP1 (0.41) | — | |
| SCHEMBL27682585 | 0.73 | SYK (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101084184-A | Cycloalkylamine derivative | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | CN | disclosed |