Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27682586 | 1.00 | SYK (0.30) | SYKKCNH2THRBMEN1KMT2A | |
| SCHEMBL28102273 | 0.97 | BTK (0.30) | — | |
| SCHEMBL27905600 | 0.85 | CA1 (0.39) | — | |
| SCHEMBL27888905 | 0.85 | CA1 (0.39) | — | |
| SCHEMBL27520063 | 0.80 | ALOX5 (0.37) | THRBMEN1KMT2A | |
| SCHEMBL9227258 | 0.79 | ALOX5 (0.39) | MEN1KMT2A | |
| SCHEMBL28014787 | 0.79 | TDP1 (0.45) | — | |
| SCHEMBL28014788 | 0.79 | TDP1 (0.45) | — | |
| SCHEMBL27766894 | 0.77 | ALOX5 (0.37) | THRBMEN1KMT2A | |
| SCHEMBL19901839 | 0.76 | SYK (0.35) | SYKTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101084184-A | Cycloalkylamine derivative | HOFFMANN LA ROCHE (CH) | 2007-12-05 | — | — | CN | disclosed |