Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364213 | 0.87 | NPC1 (0.53) | CNR2CNR1MEN1NPC1RAB9A | |
| SCHEMBL27742977 | 0.86 | LMNA (0.49) | CNR2CNR1MEN1NPC1RAB9A | |
| SCHEMBL27682759 | 0.85 | NPC1 (0.49) | CNR2CNR1MEN1NPC1RAB9A | |
| SCHEMBL27742972 | 0.85 | NPC1 (0.51) | CNR2CNR1MEN1NPC1RAB9A | |
| SCHEMBL19731925 | 0.85 | MIF (0.46) | CNR2CNR1MEN1NPC1RAB9A | |
| SCHEMBL27742966 | 0.85 | CNR1 (0.61) | CNR2CNR1MEN1NPC1RAB9A | |
| SCHEMBL27836801 | 0.85 | CNR2 (0.45) | CNR2CNR1MEN1NPC1RAB9A | |
| SCHEMBL27795718 | 0.84 | CNR1 (0.44) | CNR2CNR1MEN1NPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL27702328 | 0.84 | NPC1 (0.48) | CNR2CNR1MEN1NPC1RAB9A | |
| SCHEMBL27702044 | 0.84 | CNR2 (0.46) | CNR2CNR1MEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104945401-A | IP compounds and their use in therapy | CANCER REC TECH LTD | 2015-09-30 | — | — | CN | disclosed |
| CN-102906090-B | 1- (5-tert-butyl-2-phenyl-2H-pyrazol-3-yl) -3- [ 2-fluoro-4- (1-methyl-2-oxo-2, 3-dihydro-1H-imidazo [4,5-B ] pyridin-7-yloxy) -phenyl ] -urea and related compounds and their use in therapy | CANCER REC TECH LTD | 2015-06-24 | — | — | CN | disclosed |
| CN-102906090-A | 1- (5-tert-butyl-2-phenyl-2H-pyrazol-3-yl) -3- [ 2-fluoro-4- (1-methyl-2-oxo-2, 3-dihydro-1H-imidazo [4,5-B ] pyridin-7-yloxy) -phenyl ] -urea and related compounds and their use in therapy | CANCER REC TECH LTD | 2013-01-30 | — | — | CN | disclosed |
| CN-102026985-A | Quinazoline derivatives as RAF kinase modulators and methods and uses thereof | AMBIT BIOSCIENCES CORPORATON | 2011-04-20 | — | — | CN | disclosed |
| CN-101084217-B | Imidazo [4,5-B] pyridin-2-ones and oxazolido [4,5-B] pyridin-2-ones and analogues thereof as therapeutic compounds | CANCER REC TECH LTD | 2010-10-13 | — | — | CN | disclosed |
| CN-101316841-A | Arylmethylene urea derivative and use thereof | TORAY INDUSTRIES (JP) | 2008-12-03 | — | — | CN | disclosed |
| CN-101084217-A | Imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof as therapeutic compounds | CANCER REC TECH LTD (GB) | 2007-12-05 | — | — | CN | disclosed |