Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887724 | 0.83 | CSNK2A1 (0.37) | KMT2AMEN1NPY1RNPY2RMAPT | |
| SCHEMBL17710554 | 0.79 | CSNK2A1 (0.33) | CSNK2A1MCHR1PDE4A | |
| SCHEMBL14742168 | 0.79 | CSNK2A1 (0.47) | CSNK2A1PDE4AKMO | |
| SCHEMBL27733896 | 0.79 | CSNK2A1 (0.34) | CSNK2A1MCHR1PDE4A | |
| SCHEMBL28179624 | 0.79 | MCHR1 (0.39) | CSNK2A1MCHR1PDE4A | |
| SCHEMBL315053 | 0.77 | PDE4A (0.48) | POLBKMT2AMAPTLMNAPDE4A | |
| SCHEMBL2887418 | 0.77 | PDE4A (0.44) | POLBMAPTLMNAPDE4A | |
| SCHEMBL8492806 | 0.76 | PDE4A (0.43) | POLBKMT2AMEN1PDE4A | |
| SCHEMBL4888333 | 0.75 | CSNK2A1 (0.44) | CSNK2A1MCHR1PDE4AKMO | |
| SCHEMBL2104303 | 0.75 | CSNK2A1 (0.44) | CSNK2A1PDE4AKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101184739-A | Polycyclic * diazoles and iso- * azoles and their use as ligands for the S1P receptor | NOVARTIS AG (CH) | 2008-05-21 | — | — | CN | disclosed |