SCHEMBL17710554

SCHEMBL17710554

[c]1ccc(OC2CCC2)c(OC2CCC2)c1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 2/20 0.33
PARP10 Q53GL7 1/20 0.33
MCHR1 Q99705 2/20 0.32
PDE4A P27815 1/20 0.32
FURIN P09958 1/20 0.30
HTR1A P08908 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A3 Q01959 1/20 0.30
CYP19A1 P11511 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2887724 0.96 CSNK2A1 (0.37) CSNK2A1MCHR1PDE4ACYP19A1RECQL
SCHEMBL2885764 0.89 PDE4A (0.44) PDE4A
SCHEMBL315053 0.85 PDE4A (0.48) PDE4A
SCHEMBL2887418 0.85 PDE4A (0.44) PDE4ARECQL
SCHEMBL8492806 0.84 PDE4A (0.43) PDE4ARECQL
SCHEMBL2104303 0.83 CSNK2A1 (0.44) CSNK2A1PARP10PDE4ASLC6A2SLC6A3
SCHEMBL28757119 0.83 PDE4D (0.44) PDE4A
SCHEMBL2882597 0.81 SLC6A4 (0.43) CSNK2A1PARP10MCHR1PDE4A
SCHEMBL2882676 0.81 SLC6A4 (0.40) CSNK2A1PARP10MCHR1PDE4ARECQL
SCHEMBL12486463 0.81 PDE4A (0.40) PDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3018118-B1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2023-07-05 EP disclosed
US-10428014-B2 Base generator, base-reactive composition containing said base generator, and base generation method FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-10-01 US disclosed
EP-3018118-A1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD Wako Pure Chemical Industries, Ltd. (JP) 2016-05-11 EP disclosed
US-20160122292-A1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2016-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10428014-B2 Base generator, base-reactive composition containing said base generator, and base generation method HPRT1, GNG2, BLM CSNK2A1 2327/4885PARP10 414/4885MCHR1 2290/4885
US-20160122292-A1 BASE GENERATOR, BASE-REACTIVE COMPOSITION CONTAINING SAID BASE GENERATOR, AND BASE GENERATION METHOD GNG2, EPHX2, ARHGEF1 CSNK2A1 1023/4885PARP10 499/4885MCHR1 3607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.