Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.62 |
| ▸ | MME | P08473 | 9/20 | 0.62 |
| ▸ | CPA1 | P15085 | 3/20 | 0.62 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27935801 | 1.00 | ACE (0.62) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL4273365 | 1.00 | ACE (0.62) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL27704333 | 1.00 | ACE (0.62) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL4273366 | 1.00 | ACE (0.62) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL6445682 | 1.00 | ACE (0.62) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL29822661 | 0.97 | MME (0.60) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL30577827 | 0.95 | ACE (0.57) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL29351001 | 0.94 | ACE (0.61) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL31753582 | 0.94 | ACE (0.56) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL32679640 | 0.92 | FOLH1 (0.67) | ACEMMECPA1ACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101065354-A | Diphenylazetidinone derivates possessing cholesterol absorption inhibitory activity | ASTRAZENECA AB (SE) | 2007-10-31 | — | — | CN | disclosed |