SCHEMBL6445682

SCHEMBL6445682

CC(C)[C@H](N)C(=O)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 10/20 0.62
▸ MME P08473 9/20 0.62
▸ CPA1 P15085 3/20 0.62
▸ ACE2 Q9BYF1 3/20 0.62
▸ FOLH1 Q04609 1/20 0.60
▸ NAALAD2 Q9Y3Q0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27935801 1.00 ACE (0.62) ACEMMECPA1ACE2FOLH1
SCHEMBL27704335 1.00 ACE (0.62) ACEMMECPA1ACE2FOLH1
SCHEMBL4273365 1.00 ACE (0.62) ACEMMECPA1ACE2FOLH1
SCHEMBL27704333 1.00 ACE (0.62) ACEMMECPA1ACE2FOLH1
SCHEMBL4273366 1.00 ACE (0.62) ACEMMECPA1ACE2FOLH1
SCHEMBL29822661 0.97 MME (0.60) ACEMMECPA1ACE2FOLH1
SCHEMBL30577827 0.95 ACE (0.57) ACEMMECPA1ACE2FOLH1
SCHEMBL29351001 0.94 ACE (0.61) ACEMMECPA1ACE2FOLH1
SCHEMBL31753582 0.94 ACE (0.56) ACEMMECPA1ACE2FOLH1
SCHEMBL32679640 0.92 FOLH1 (0.67) ACEMMECPA1ACE2FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1234576-C packaging and painting unit OREAL (FR) 2006-01-04 — — CN disclosed
US-6945723-B1 Packaging and application device L'ORÉAL (FR) 2005-09-20 — — US disclosed
CN-1162308-C Assembly of packing and using liquid-powder �ź㴫 2004-08-18 — — CN disclosed
US-6682244-B2 Devices and methods for dispensing L'OREAL S.A. (FR) 2004-01-27 — — US disclosed
US-20020041854-A1 Cosmetic compositions in powder form comprising a binder, and make-up and cosmetic care methods L'OREAL S.A. (FR) 2002-04-11 — — US disclosed
US-20020034480-A1 Make-up compositions comprising a binder phase, and make-up methods L'OREAL, S.A. (FR) 2002-03-21 — — US disclosed
US-20020021932-A1 Devices and methods for dispensing L'OREAL S.A. (FR) 2002-02-21 — — US disclosed
CN-1324749-A Assembly of packing and using liquid-powder OREAL (FR) 2001-12-05 — — CN disclosed
CN-1290641-A packaging and painting unit OREAL (FR) 2001-04-11 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020034480-A1 Make-up compositions comprising a binder phase, and make-up methods TTR, GRN, MB ACE 1352/4885MME 3606/4885CPA1 3671/4885
US-20020041854-A1 Cosmetic compositions in powder form comprising a binder, and make-up and cosmetic care methods CUTA, LAGE3, MITF ACE 3485/4885MME 4307/4885CPA1 4109/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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