Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144579 | 0.95 | TDP1 (0.41) | ALDH1A1TSHRTHRBTDP1TP53 | |
| SCHEMBL7094322 | 0.93 | TDP1 (0.42) | ALDH1A1TSHRTHRBTDP1TP53 | |
| SCHEMBL328720 | 0.85 | ALDH1A1 (0.43) | ALDH1A1TSHRTDP1TP53HIF1A | |
| SCHEMBL9439268 | 0.83 | — | — | |
| SCHEMBL14827534 | 0.83 | TDP1 (0.44) | ALDH1A1TSHRTDP1TP53HIF1A | |
| SCHEMBL2571406 | 0.82 | ALDH1A1 (0.42) | ALDH1A1TSHRTHRBTDP1TP53 | |
| SCHEMBL27705203 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRTHRBTP53HIF1A | |
| SCHEMBL13111366 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBTDP1TP53 | |
| SCHEMBL18746205 | 0.80 | TDP1 (0.43) | ALDH1A1TSHRTHRBTDP1TP53 | |
| SCHEMBL2293338 | 0.78 | TDP1 (0.42) | ALDH1A1TSHRTDP1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101198756-B | Sound insulation material, load-bearing floor made of sound insulation material and preparation method of floor | PIRELLI & C SPA | 2010-10-06 | — | — | CN | disclosed |
| CN-101198756-A | Preparation method of sound-insulation load-bearing floor | PIRELLI & C SPA (IT) | 2008-06-11 | — | — | CN | disclosed |