Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2948935 | 0.81 | CA1 (0.43) | TRPV1 | |
| SCHEMBL2959317 | 0.81 | KDM4E (0.44) | — | |
| SCHEMBL5500652 | 0.77 | CA1 (0.41) | TRPV1 | |
| SCHEMBL5505542 | 0.76 | — | — | |
| SCHEMBL2958972 | 0.76 | MEN1 (0.51) | SMN1; SMN2TRPV1 | |
| SCHEMBL13387445 | 0.74 | FAAH (0.58) | TSHRSMN1; SMN2FAAH | |
| SCHEMBL2948213 | 0.74 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL5272637 | 0.73 | TRPV1 (0.48) | TRPV1 | |
| SCHEMBL5282552 | 0.73 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL13238790 | 0.72 | TRPV1 (0.37) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101142174-A | Novel compounds as vanilloid receptor antagonists, isomers thereof or pharmaceutically acceptable salts thereof; and pharmaceutical compositions comprising the same | AMOREPACIFIC CORP (KR) | 2008-03-12 | — | — | CN | disclosed |