Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA4 | P22748 | 3/20 | 0.52 |
| ▸ | CA6 | P23280 | 3/20 | 0.52 |
| ▸ | CA5A | P35218 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CA9 | Q16790 | 3/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | F13A1 | P00488 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | THPO | P40225 | 2/20 | 0.52 |
| ▸ | CASP2 | P42575 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Spermine SCHEMBL27905574 | 0.78 | CA12 (0.77) | CA12CA2CA4CA6CA5A | |
| SCHEMBL12927025 | 0.76 | CA12 (0.57) | CA12CA2CA4CA6CA5A | |
| SCHEMBL2601753 | 0.75 | CHRM2 (0.36) | CA12CA2CA4CA6CA5A | |
| SCHEMBL2601752 | 0.75 | — | — | |
| Spermine SCHEMBL27722730 | 0.75 | CA12 (0.81) | CA12CA2CA4CA6CA5A | |
| SCHEMBL19866282 | 0.74 | CA12 (0.62) | CA12CA2CA4CA6CA5A | |
| SCHEMBL12927133 | 0.74 | CA12 (0.59) | CA12CA2CA4CA6CA5A | |
| SCHEMBL28195931 | 0.73 | CASP2 (0.77) | CA12CA2CA4CA6CA5A | |
| SCHEMBL21799926 | 0.72 | CA12 (0.56) | CA12CA2CA4CA6CA5A | |
| SCHEMBL21799948 | 0.72 | CA12 (0.56) | CA12CA2CA4CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103080313-A | Conjugates, particles, compositions, and related methods | CERULEAN PHARMA INC | 2013-05-01 | — | — | CN | claimed |
| CN-108474007-A | Methods of producing animals comprising germline genetic modifications | 联邦科学技术研究组织 | 2018-08-31 | — | — | CN | disclosed |
| CN-104619848-A | Cell transfection method | COMMW SCIENT IND RES ORG | 2015-05-13 | — | — | CN | disclosed |
| CN-103080313-A | Conjugates, particles, compositions, and related methods | CERULEAN PHARMA INC | 2013-05-01 | — | — | CN | disclosed |
| CN-101208438-A | Methods of treating inflammatory diseases using double-stranded ribonucleic acids | NASTECH PHARM CO (US) | 2008-06-25 | — | — | CN | disclosed |