SCHEMBL27705671

SCHEMBL27705671

O=C(O)CCC(=O)OC(=O)CCC(=O)OC(=O)CCC(=O)O.[NaH].[NaH].[NaH].[NaH]

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.56
EGLN1 Q9GZT9 4/20 0.56
ALKBH5 Q6P6C2 1/20 0.56
SUCNR1 Q9BXA5 1/20 0.56
KDM5C P41229 3/20 0.50
PHF8 Q9UPP1 3/20 0.50
KDM2A Q9Y2K7 3/20 0.50
KDM6B O15054 2/20 0.50
ALDH1A1 P00352 1/20 0.48
SLC15A2 Q16348 1/20 0.43
MAPK1 P28482 1/20 0.43
SLC13A3 Q8WWT9 1/20 0.43
OR51E2 Q9H255 1/20 0.43
SLC22A6 Q4U2R8 1/20 0.42
TSHR P16473 4/20 0.40
NFKB1 P19838 1/20 0.40
PMP22 Q01453 1/20 0.40
KDM4E B2RXH2 2/20 0.39
FOLH1 Q04609 1/20 0.39
GABRR1 P24046 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2218408 1.00 LMNA (0.56) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL27749051 1.00 LMNA (0.56) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL288701 0.97 LMNA (0.60) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL1992862 0.97 LMNA (0.60) LMNAEGLN1ALKBH5SUCNR1KDM5C
Ammonia Solution, Strong SCHEMBL28163791 0.94 LMNA (0.56) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL5633908 0.88 EGLN1 (0.50) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL429060 0.88 LMNA (0.53) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL2209527 0.88 TSHR (0.54) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL6906105 0.88 LMNA (0.50) LMNAEGLN1ALKBH5SUCNR1KDM5C
SCHEMBL100416 0.86 TSHR (0.55) LMNAEGLN1ALKBH5SUCNR1KDM5C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108728230-A steam turbine lubricating oil composition 苏州福瑞斯德新材料科技有限公司 2018-11-02 CN disclosed
CN-101200755-A Bacterium identification reagent kit as well as preparation method and uses thereof UNIV SOUTH CHINA AGRICULT (CN) 2008-06-18 CN disclosed