Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | FABP7 | O15540 | 2/20 | 0.38 |
| ▸ | FABP3 | P05413 | 2/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27515302 | 0.84 | HDAC8 (0.41) | MAPTSLC6A2SLC6A4HDAC8HDAC6 | |
| SCHEMBL27483135 | 0.84 | HDAC8 (0.41) | HDAC8HDAC6HDAC1 | |
| SCHEMBL27467155 | 0.83 | MDM2 (0.40) | CHRM3 | |
| SCHEMBL17731122 | 0.75 | MAPT (0.46) | MAPTPKMHDAC8HDAC6HDAC1 | |
| SCHEMBL28635739 | 0.74 | FABP5 (0.57) | SLC6A2SLC6A4CHRM2CHRM4CHRM5 | |
| SCHEMBL28635740 | 0.74 | FABP5 (0.57) | SLC6A2SLC6A4CHRM2CHRM4CHRM5 | |
| SCHEMBL28644515 | 0.74 | FABP5 (0.57) | SLC6A2SLC6A4CHRM2CHRM4CHRM5 | |
| SCHEMBL23996149 | 0.73 | AKR1C3 (0.48) | CHRM4 | |
| SCHEMBL10671395 | 0.73 | MEN1 (0.47) | KCNQ3KCNQ2MEN1KMT2A | |
| SCHEMBL10671392 | 0.73 | MEN1 (0.47) | KCNQ3KCNQ2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146779-A | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AG (DE) | 2008-03-19 | — | — | CN | disclosed |